|Real Name:||Ophelia Sarkissan|
|First Appearance:||Target X|
|Voiced by:||Lisa Ann Beley|
- "When they are done with her, X-23 will be the perfect weapon she was designed to be. One without emotion or free will."
Viper is the supreme commander of HYDRA. As Madame Hydra, she took control of H.Y.D.R.A.'s New York branch, and from there the rest of H.Y.D.R.A.'s organization. Viper is a master of poisons and is immune to almost all toxins. In fact, she uses a poisonous lipstick to give her foes a literal "Kiss of Death".
She is the one who originally sponsored the creation of X-23, a clone of Wolverine, which was directed by H.Y.D.R.A. scientist Deborah Risman, who would eventually defect to S.H.I.E.L.D.. Among H.Y.D.R.A.'s agents are Gauntlet and Omega Red, whom she uses to do her dirty work for her.
As for Madame Hydra herself, like a true bully, she preys on those weaker than she, and once cornered or placed in a dangerous situation, she typically panics. She has a great deal of intelligence, as she was able to plan a trap that intended to use Wolverine as bait to recapture X-23. However, X-23 was finally able to trap her aboard a hover craft, which she then destroyed. While X-23 escapes the craft before its explosion and subsequent crash, whether Viper survived the crash or not is unknown.
- In the Marvel Comics, Wolverine married Viper as part of a debt. Fortunately, the marriage didn't last long.